Cyanide & Happiness started out as a webcomic, then the guys behind it—Kris Wilson, Rob DenBleyker, Matt Melvin, and Dave McElfatrick—put out the occasional animated short (I'm sure you can get greetings cards too and probably tees and mugs, etc), but last year they launched a Kickstarter campaign to fund a series.
It was successful, like way successful, achieving three times what they needed and meant they could produce a series of 10 minute episodes of a fully independent, with no meddling censorship, Cyanide & Happiness show.
Episode one is now finally available to watch. It's a sketch comedy so it's ten minutes of animated mayhem with the goal being to "extract the human excretion known as laughter from your face hole via fast-paced weird comedy."
It pretty much lives up to that description. The show will now run at one episode a week of an eleven episode season.